Asami T, Min Y K, Nakano T, Matsuyama T, Murofushi N, Yamaguchi I, Yoshida S
RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan.
Bioorg Med Chem Lett. 2000 Jul 17;10(14):1571-4. doi: 10.1016/s0960-894x(00)00302-4.
Replacing the 4'-carbonyl group of abscisic acid with a methoxy group does not affect the abscisic acid (ABA)-like activities of the product in barley aleurone protoplasts, although the reduction of ABA to 4'-hydroxyl derivatives significantly reduces the ABA-like activity of the products. This suggests that methoxy derivatives of abscisic acid might be used to produce probes for ABA binding proteins.
用甲氧基取代脱落酸的4'-羰基不会影响该产物在大麦糊粉层原生质体中的脱落酸(ABA)样活性,尽管将ABA还原为4'-羟基衍生物会显著降低产物的ABA样活性。这表明脱落酸的甲氧基衍生物可能用于制备ABA结合蛋白的探针。