Borrmann Ⅳ型胃癌患者根治性切除的手术结果，特别提及淋巴结转移范围

Surgical outcome of curative resection in patients with Borrmann type IV gastric carcinoma with particular reference to the extent of lymph node metastasis.

作者信息

Kikuchi S, Hiki Y, Tsutsumi O, Kobayashi N, Tsukamoto H, Shimao H, Sakakibara Y, Kakita A

机构信息

Department of Surgery, School of Medicine, Kitasato University, Kanagawa, Japan.

出版信息

Hepatogastroenterology. 2000 May-Jun;47(33):890-2.

PMID:10919055

Abstract

BACKGROUND/AIMS: The prognosis after curative resection for Borrmann type IV carcinoma, according to the extent of lymph node metastasis, is poorly understood.

METHODOLOGY

The surgical outcome of curative resection was examined in 78 patients with T2-T3 Borrmann type IV gastric carcinomas, with particular reference to the extent of lymph node metastasis.

RESULTS

The 5-year survival rate was 35.7% for the n0 patients, 27.8% for the n1 patients, 18.2% for the n2 patients and 0% for the n3 or n4 patients. The survival curve for the n3 or n4 patients differed significantly from those of the n0 (P < 0.0001), n1 (P = 0.0009) and n2 (P = 0.0203) patients. However, no other statistically significant differences between the curves were found.

CONCLUSIONS

The results of the present study indicate that patients with Borrmann type IV carcinoma of the stomach may indeed be cured by curative surgery, and that the surgical outcome of this disease does not depend on the extent of lymph node metastasis under curative resection if lymph node metastasis is restricted to the n2 lymph nodes.

摘要

背景/目的：关于Borrmann IV型癌根治性切除术后的预后，根据淋巴结转移程度的情况，目前了解甚少。

方法

对78例T2 - T3期Borrmann IV型胃癌患者根治性切除的手术结果进行了研究，特别关注淋巴结转移程度。

结果

n0期患者的5年生存率为35.7%，n1期患者为27.8%，n2期患者为18.2%，n3或n4期患者为0%。n3或n4期患者的生存曲线与n0期（P < 0.0001）、n1期（P = 0.0009）和n2期（P = 0.0203）患者的生存曲线有显著差异。然而，曲线之间未发现其他具有统计学意义的差异。