Wollmer P, Valind S, Landoni C, Fazio F
Kliniskt fysiologiska avdelningen, Universitetssjukhuset MAS, Malmö.
Ugeskr Laeger. 2000 Jul 3;162(27):3846-8.
Glucose consumption in tissue can be measured using positron emission tomography (PET) and 18F-deoxyglucose (18FDG). Malignant tumors rely largely on anaerobic glycolysis and show very rapid glucose consumption, and can therefore be imaged using PET and 18FDG. PET has been shown to be useful in the evaluation of patients with e.g. lung cancer, colo-rectal cancer, malignant melanoma and malignant lymphoma, in terms of both diagnostic accuracy and cost-effectiveness. The clinical use of PET for workup of cancer patients is increasing rapidly in North America as well as in the European Union, but Sweden is lagging behind.
组织中的葡萄糖消耗可以使用正电子发射断层扫描(PET)和18F-脱氧葡萄糖(18FDG)来测量。恶性肿瘤在很大程度上依赖无氧糖酵解,并且显示出非常快速的葡萄糖消耗,因此可以使用PET和18FDG进行成像。PET已被证明在评估例如肺癌、结直肠癌、恶性黑色素瘤和恶性淋巴瘤患者方面,在诊断准确性和成本效益方面都很有用。在北美以及欧盟,PET在癌症患者检查中的临床应用正在迅速增加,但瑞典却落后了。