Simpson R W, Kast S J
Box Hill Hospital, Melbourne, VIC.
Med J Aust. 2000 Jun 5;172(11):537-40. doi: 10.5694/j.1326-5377.2000.tb124099.x.
To investigate whether 2-hour postprandial blood glucose levels up to 8.0 mmol/L affect maternal or neonatal outcomes in pregnancies complicated by gestational diabetes mellitus (GDM).
Retrospective analysis of data collated by the Victorian Perinatal Data Collection Unit.
394 GDM women and 394 control women matched for age and country of birth who gave birth at a university teaching hospital, 1991-1997.
Maternal--hypertension/pre-eclampsia, obstetric intervention, gestation at delivery, length of hospital stay; neonatal--Apgar scores, time to establish respiration, birthweight, macrosomia, large or small for gestational age (LGA or SGA), fetopelvic disproportion, jaundice, hypoglycaemia.
For most outcome measures there were no statistically significant differences between the GDM and control groups. However, in the GDM group, gestation was shorter, hospital stays longer and delivery interventions more common.
Our study suggests that maternal and neonatal outcomes in GDM women are comparable with those of women without GDM when 2-hour postprandial glucose levels of up to 8mmol/L are maintained. This is 1.0 mmol/L higher than the current Australian Diabetes in Pregnancy Society recommendation.
探讨餐后2小时血糖水平高达8.0 mmol/L是否会影响妊娠期糖尿病（GDM）孕妇的母婴结局。
对维多利亚围产期数据收集单位整理的数据进行回顾性分析。
1991 - 1997年在一家大学教学医院分娩的394例GDM孕妇和394例年龄及出生国家匹配的对照孕妇。
母亲——高血压/先兆子痫、产科干预、分娩孕周、住院时间；新生儿——阿氏评分、建立呼吸时间、出生体重、巨大儿、大于或小于胎龄（LGA或SGA）、头盆不称、黄疸、低血糖。
对于大多数观察指标，GDM组和对照组之间无统计学显著差异。然而，GDM组的孕周较短，住院时间较长，分娩干预更常见。
我们的研究表明，当餐后2小时血糖水平维持在高达8mmol/L时，GDM孕妇的母婴结局与非GDM孕妇相当。这比当前澳大利亚妊娠糖尿病协会的建议值高1.0 mmol/L。
