男性型秃发
Male pattern baldness.
作者信息
Hogan D J, Chamberlain M
机构信息
Section of Dermatology, Louisiana State University School of Medicine, Shreveport 71130-3932, USA.
出版信息
South Med J. 2000 Jul;93(7):657-62.
BACKGROUND
Male pattern baldness, or androgenetic alopecia (AGA) in men, occurs with varying severity and age of onset. Two new treatments widely available as alternatives to 2% minoxidil are 1 mg finasteride and topical 5% minoxidil. Finasteride is a 5 alpha-reductase inhibitor available by prescription only; 5% minoxidil is available over the counter.
METHODS
We searched MEDLINE to identify all articles on AGA and its pharmacologic therapies.
RESULTS
We found limited information on AGA in peer review medical journals. Associated diseases include psychologic disorders and coronary heart disease. Hair growth is unpredictable and limited for all pharmacologic therapies, with the vast majority of treatment studies being industry sponsored.
CONCLUSION
AGA is not easy to treat. Finasteride and 5% minoxidil offer new therapeutic options to the balding man. Treatment options may improve as new drugs are further investigated.
背景
男性型秃发，即男性雄激素性脱发（AGA），其严重程度和发病年龄各不相同。两种广泛可用的替代2%米诺地尔的新疗法是1毫克非那雄胺和外用5%米诺地尔。非那雄胺是一种5α还原酶抑制剂，仅凭处方可得；5%米诺地尔可非处方购买。
方法
我们检索了MEDLINE以识别所有关于AGA及其药物治疗的文章。
结果
我们在同行评审医学期刊上发现关于AGA的信息有限。相关疾病包括心理障碍和冠心病。所有药物治疗的头发生长都是不可预测的且有限的，绝大多数治疗研究由行业赞助。
结论
AGA不易治疗。非那雄胺和5%米诺地尔为脱发男性提供了新的治疗选择。随着新药的进一步研究，治疗选择可能会改善。
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