Muzumdar D P, Misra B K, Bhaduri A S
Department of Neurosurgery, P.D. Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai, India.
Neurol Med Chir (Tokyo). 2000 Jul;40(7):372-9. doi: 10.2176/nmc.40.372.
A 45-year-old male presented with a rare pineal region cavernoma. Magnetic resonance (MR) imaging confirmed the preoperative diagnosis. The tumor was totally excised. The patient was subsequently cured. Analysis of 15 reported cases found a slight female preponderance. The second and third decades were the most common age group. The course of pineal cavernomas can be complicated by hemorrhage, occlusion of cerebrospinal fluid pathways, and focal neurological and neuroendocrine symptoms but no specific clinical features. However, MR imaging has high sensitivity and the specificity for the diagnosis of pineal cavernoma. Total microneurosurgical excision is the treatment of choice, and patients had an excellent outcome. Stereotactic biopsy can be potentially dangerous because of the risk of hemorrhage. The use of radiosurgery requires evaluation of long-term risks and safe dose levels. Total excision of the pineal cavernoma using microsurgical techniques is the choice of treatment in young and healthy patients since there is an increased risk of recurrent hemorrhage and progressive neurological decline. A conservative approach is preferred in older patients.
一名45岁男性患有罕见的松果体区海绵状血管瘤。磁共振成像(MR)证实了术前诊断。肿瘤被完全切除。患者随后治愈。对15例报告病例的分析发现女性略占优势。第二和第三个十年是最常见的年龄组。松果体海绵状血管瘤的病程可能因出血、脑脊液通路阻塞以及局灶性神经和神经内分泌症状而复杂化,但没有特定的临床特征。然而,MR成像对松果体海绵状血管瘤的诊断具有高敏感性和特异性。显微神经外科全切术是首选治疗方法,患者预后良好。立体定向活检由于有出血风险可能具有潜在危险性。使用放射外科需要评估长期风险和安全剂量水平。对于年轻健康患者,采用显微外科技术全切松果体海绵状血管瘤是治疗选择,因为复发性出血和进行性神经功能衰退的风险增加。老年患者首选保守治疗方法。