Iglseder B, Patt C M, Raffer E, Hess-Eberle I, Huemer M, Staffen W, Ladurner G
Neurologische Abteilung, Christian-Doppler-Klinik (LNK) Salzburg, Osterreich.
Ultraschall Med. 2000 Jun;21(3):107-11. doi: 10.1055/s-2000-3792.
To evaluate the diagnostic advantages of Levovist for contrast enhancement of intracranial arteries in a routine clinical setting.
Routine cerebrovascular extracranial Doppler- and duplex-sonography was performed in 3990 patients (1791 female, 2189 male, mean age 50.4 years). In addition 879 trans-temporal, 990 trans-foraminal and 99 trans-orbital trans-cranial colour-coded duplex investigations were performed on these patients. Signal quality was classified in the categories: 'no signal', 'insufficient signal' and 'sufficient signal'. Patients classified as having 'no' or 'insufficient' signal quality underwent an additional examination after application of Levovist.
879 patients underwent trans-temporal examination. In 89 (9.1%) of these patients signal quality in the trans-temporal examination proved to be insufficient, thus indicating the use of Levovist. 346 of the examined vessels (72%) were originally classified as showing 'no signal'; this number could be reduced to 82 (23.9%) after applying Levovist. Of the 99 arteries (21%) falling into the category 'insufficient signal', only 4 (4%) did not show signal improvement after application of Levovist. 990 patients were examined by the trans-foraminal approach, and Levovist was given to just 26 patients (2.6%). Without enhancement, 20 basilar arteries (77%) showed 'no' or 'insufficient' signal, whereas after injecting Levovist only 4 (13.25%) remained in these categories. Of 13 vertebral arteries (25%) with 'no' or 'insufficient' signal intensity, 3 (5.8%) showed no improvement in imaging quality after application of Levovist.
Imaging problems of intracranial arteries are dramatically reduced by Levovist.
评估在常规临床环境中，声诺维对颅内动脉增强造影的诊断优势。
对3990例患者（1791例女性，2189例男性，平均年龄50.4岁）进行常规脑血管颅外多普勒和双功超声检查。此外，对这些患者进行了879次经颞、990次经孔和99次经眶的经颅彩色编码双功检查。信号质量分为“无信号”、“信号不足”和“信号充足”三类。信号质量被分类为“无”或“不足”的患者在应用声诺维后接受了额外检查。
879例患者接受了经颞检查。其中89例（9.1%）经颞检查的信号质量被证明不足，因此表明需要使用声诺维。最初，346条被检查血管（72%）被分类为显示“无信号”；应用声诺维后，这一数字可降至82条（23.9%）。在99条（21%）属于“信号不足”类别的动脉中，应用声诺维后只有4条（4%）没有显示信号改善。990例患者通过经孔途径进行检查，仅26例患者（2.6%）给予了声诺维。在未增强的情况下，20条基底动脉（77%）显示“无”或“不足”信号，而注射声诺维后，只有4条（13.25%）仍属于这些类别。在13条椎动脉（25%）信号强度为“无”或“不足”的情况下，应用声诺维后，3条（5.8%）的成像质量没有改善。
声诺维可显著减少颅内动脉的成像问题。
