Friberg T R
University of Pittsburgh School of Medicine, and the Eye and Ear Institute of Pittsburgh, PA, USA.
Ophthalmic Surg Lasers. 1999 Jul-Aug;30(7):518-22.
Some patients with macular disease, because of physical infirmity or disability, cannot be treated with laser photocoagulation using a typical slit lamp delivery system. The purpose of this study was to determine whether the binocular indirect ophthalmoscope could be used to deliver treatment to the macula when photocoagulation would otherwise be very difficult, if not impossible, to perform.
Ten eyes of 10 patients who could not sit for slit lamp laser delivery were treated with binocular indirect ophthalmoscope laser photocoagulation over a 36 month period. Eight had subfoveal choroidal neovascularization (CNV) from age-related macular degeneration (AMD), and 2 patients had clinically significant macular edema (CSME) from diabetes mellitus. Argon laser photocoagulation was delivered to the choroidal neovascular membrane in patients with exudative AMD, and a grid treatment was given to eyes with diabetic macular edema.
Six of 8 patients with exudative AMD were successfully treated with eradication of the CNV. Two required retreatment within 6 months of original treatment. Both patients with CSME had resolution of their edema at 3 and 6 months after treatment. Best corrected visual acuity did not change by more than 2 Snellen lines in any patient with CNV and 1 Snellen line in patients with CSME. No complications of treatment were encountered.
In certain circumstances, laser photocoagulation of the macula using the indirect ophthalmoscope laser delivery system should be considered when more conventional treatment strategies cannot be implemented.
一些黄斑疾病患者,由于身体虚弱或残疾,无法使用典型的裂隙灯传输系统进行激光光凝治疗。本研究的目的是确定在光凝治疗否则将非常困难甚至无法进行的情况下,双目间接检眼镜是否可用于黄斑区的治疗。
在36个月期间,对10名无法坐于裂隙灯激光治疗的患者的10只眼睛进行了双目间接检眼镜激光光凝治疗。8例患有年龄相关性黄斑变性(AMD)引起的黄斑下脉络膜新生血管(CNV),2例患有糖尿病引起的具有临床意义的黄斑水肿(CSME)。对渗出性AMD患者的脉络膜新生血管膜进行氩激光光凝,对糖尿病性黄斑水肿患者的眼睛进行格栅治疗。
8例渗出性AMD患者中有6例成功治疗,CNV消除。2例在初次治疗后6个月内需要再次治疗。2例CSME患者在治疗后3个月和6个月时水肿消退。任何CNV患者的最佳矫正视力变化不超过2行Snellen视力表,CSME患者不超过1行Snellen视力表。未遇到治疗并发症。
在某些情况下,当无法实施更传统的治疗策略时,应考虑使用间接检眼镜激光传输系统对黄斑进行激光光凝治疗。