Izmerov N F, Dueva L A, Milishnikova V V
Med Tr Prom Ekol. 2000(6):1-6.
The authors determined pneumoconiosis as a chronic diffuse or diffuse and granulomatous pneumonitis with pulmonary fibrosis. The article deals with identification of lymphocytes subpopulations through monoclonal antibodies, details peculiarities of cellular immunity in pneumoconiosis patients, contains new data on LgE-dependent inflammatory mechanisms including specific response to industrial dust allergens. Discussion covers ways of immune correction therapy and immune prophylactics in accordance with phases of body response to homotoxins produced due to exogenous dust load.
作者将尘肺病定义为伴有肺纤维化的慢性弥漫性或弥漫性肉芽肿性肺炎。本文论述了通过单克隆抗体识别淋巴细胞亚群,详述了尘肺病患者细胞免疫的特点,包含了关于IgE依赖性炎症机制的新数据,包括对工业粉尘过敏原的特异性反应。讨论内容涵盖了根据机体对外源性粉尘负荷产生的同种毒素反应阶段进行免疫矫正治疗和免疫预防的方法。