Oztürkcan S, Içağasioğlu D, Akyol M, Cevit O
Department of Dermatology, Medical Faculty of Celal Bayar University, Manisa, Turkey.
J Dermatol. 2000 Jul;27(7):475-7. doi: 10.1111/j.1346-8138.2000.tb02210.x.
Acrodermatitis enteropathica is a rare hereditary disorder affecting zinc metabolism that is characterized by dermatitis, alopecia, gastrointestinal disturbances, eye infections, and growth failure. We report a 17-month-old girl with acrodermatitis enteropathica. Physical examination showed a cutaneous eruption consisting of vesiculobullous and psoriasiform skin lesions symmetrically distributed in the perioral, acral, and perineal areas. Her plasma zinc level was decreased (75 micrograms/dl), but within the normal range (60.00-135.00 micrograms/dl). The patient was given zinc sulfate 50 mg/day. At the end of two months, she had significantly improved.
肠病性肢端皮炎是一种罕见的遗传性疾病,影响锌代谢,其特征为皮炎、脱发、胃肠道紊乱、眼部感染和生长发育迟缓。我们报告了一名患有肠病性肢端皮炎的17个月大女孩。体格检查显示皮肤疹,由水疱大疱性和银屑病样皮肤病变组成,对称分布于口周、肢端和会阴区域。她的血浆锌水平降低(75微克/分升),但在正常范围内(60.00 - 135.00微克/分升)。给予患者硫酸锌50毫克/天。两个月后,她有了显著改善。