Klenin K, Langowski J
Division Biophysics of Macromolecules, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
Biopolymers. 2000 Oct 15;54(5):307-17. doi: 10.1002/1097-0282(20001015)54:5<307::AID-BIP20>3.0.CO;2-Y.
We describe four previously unpublished methods allowing the computation of the writhe for a supercoiled DNA molecule modeled by a polymer chain consisting of straight segments. These methods are compared with each other in terms of computational efficiency and the scope of their applicability is discussed.
我们描述了四种此前未发表的方法，这些方法可用于计算由直链段组成的聚合物链模拟的超螺旋DNA分子的缠绕数。对这些方法的计算效率进行了相互比较，并讨论了它们的适用范围。
