超螺旋DNA建模中螺旋数的计算。
Computation of writhe in modeling of supercoiled DNA.
作者信息
Klenin K, Langowski J
机构信息
Division Biophysics of Macromolecules, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
出版信息
Biopolymers. 2000 Oct 15;54(5):307-17. doi: 10.1002/1097-0282(20001015)54:5<307::AID-BIP20>3.0.CO;2-Y.
Abstract
We describe four previously unpublished methods allowing the computation of the writhe for a supercoiled DNA molecule modeled by a polymer chain consisting of straight segments. These methods are compared with each other in terms of computational efficiency and the scope of their applicability is discussed.
摘要
我们描述了四种此前未发表的方法，这些方法可用于计算由直链段组成的聚合物链模拟的超螺旋DNA分子的缠绕数。对这些方法的计算效率进行了相互比较，并讨论了它们的适用范围。
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