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新千年伊始生殖生物学与遗传学中的专业及伦理挑战

[Professional and ethical challenges in reproductive biology and genetics at the beginning of the ne millennium].

作者信息

Papp Z, Urbancsek J

机构信息

I. Szülészeti és Nógyógyászati Klinika, Altalános Orvostudományi Kar, Semmelweis Egyetem, Budapest.

出版信息

Orv Hetil. 2000 Jun 11;141(24):1327-42.

Abstract

About 15 to 20 percent of couples are infertile. Developments in reproductive biology have enabled treatment of these couples by means of assisted reproduction. In a broader sense, assisted reproductive technologies involve all methods aiming to restore impaired reproductive function. Preimplantation genetic testing, a new form of prenatal diagnosis, is a result of convergency in the development of assisted reproduction and genetics, and allows couples at risk of transferring hereditary diseases to their offspring to diagnose such abnormalities as early as immediately before or after conception. This article describes technologies of assisted reproduction and preimplantation genetic diagnosis, and discusses ethical as well as legal issues in reproductive medicine.

摘要

约15%至20%的夫妇存在不孕问题。生殖生物学的发展使得通过辅助生殖手段治疗这些夫妇成为可能。从更广泛的意义上讲,辅助生殖技术涵盖了所有旨在恢复受损生殖功能的方法。植入前基因检测是一种新的产前诊断形式,它是辅助生殖与遗传学发展融合的成果,使有将遗传性疾病传给后代风险的夫妇能够在受孕前后尽早诊断此类异常情况。本文介绍了辅助生殖技术和植入前基因诊断,并讨论了生殖医学中的伦理和法律问题。

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