Bloomberg J J, Merkle L A, Barry S R, Huebner W P, Cohen H S, Mueller S A, Fordice J
Life Sciences Research Laboratories, NASA Johnson Space Center, Houston, TX 77058, USA.
J Vestib Res. 2000;10(2):75-86.
The goal of the present study was to determine if adaptive modulation of vestibulo-ocular reflex (VOR) function is associated with commensurate alterations in manual target localization. To measure the effects of adapted VOR on manual responses we developed the Vestibular-Contingent Pointing Test (VCP). In the VCP test, subjects pointed to a remembered target following passive whole body rotation in the dark. In the first experiment, subjects performed VCP before and after wearing 0.5X minifying lenses that adaptively attenuate horizontal VOR gain. Results showed that adaptive reduction in horizontal VOR gain was accompanied by a commensurate change in VCP performance. In the second experiment, bilaterally labyrinthine deficient (LD) subjects were tested to confirm that vestibular cues were central to the spatial coding of both eye and hand movements during VCP. LD subjects performed significantly worse than normal subjects. These results demonstrate that adaptive change in VOR can lead to alterations in manual target localization.
本研究的目的是确定前庭眼反射（VOR）功能的适应性调节是否与手动目标定位的相应改变相关。为了测量适应性VOR对手动反应的影响，我们开发了前庭条件指向测试（VCP）。在VCP测试中，受试者在黑暗中被动全身旋转后指向记忆中的目标。在第一个实验中，受试者在佩戴0.5倍缩小透镜前后进行VCP测试，该透镜可自适应衰减水平VOR增益。结果表明，水平VOR增益的适应性降低伴随着VCP表现的相应变化。在第二个实验中，对双侧迷路缺陷（LD）受试者进行测试，以确认前庭线索对于VCP期间眼睛和手部运动的空间编码至关重要。LD受试者的表现明显比正常受试者差。这些结果表明，VOR的适应性变化可导致手动目标定位的改变。
