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体外受精前对输卵管积水进行烧灼是一种有效的外科治疗方法,与提高妊娠率相关。

Cauterization of hydrosalpinges before in vitro fertilization is an effective surgical treatment associated with improved pregnancy rates.

作者信息

Stadtmauer L A, Riehl R M, Toma S K, Talbert L M

机构信息

North Carolina Center for Reproductive Medicine, Cary 27511, USA.

出版信息

Am J Obstet Gynecol. 2000 Aug;183(2):367-71. doi: 10.1067/mob.2000.107671.

Abstract

OBJECTIVE

Our purpose was to determine whether proximal tubal cauterization is an effective method of reversing the decreased pregnancy rates seen in patients undergoing in vitro fertilization-embryo transfer with hydrosalpinges present.

STUDY DESIGN

We studied a group of 94 patients with tubal factor infertility. Sixty patients had hydrosalpinges documented by either hysterosalpingography or laparoscopy, or both. Forty-five had surgical treatment of hydrosalpinges by salpingectomy or by proximal tubal cauterization. In vitro fertilization-embryo transfer was performed within 3 months after surgery. Pregnancy and implantation rates were compared.

RESULTS

Patients with hydrosalpinx had significantly decreased clinical pregnancy and implantation rates per cycle (14% and 8%, respectively) compared with those of patients undergoing proximal tubal cauterization before the in vitro fertilization cycle (73% and 36%, respectively). These pregnancy and implantation rates are comparable with those found in patients with tubal factor infertility without hydrosalpinges (53% and 22%, respectively), as well as in salpingectomy-treated patients (46% and 24%, respectively).

CONCLUSIONS

Proximal tubal cauterization is effective in reversing the adverse effects of hydrosalpinges.

摘要

目的

我们的目的是确定输卵管近端烧灼术是否是一种有效的方法,可逆转在患有输卵管积水的体外受精-胚胎移植患者中观察到的妊娠率下降情况。

研究设计

我们研究了一组94例输卵管因素不孕症患者。60例患者通过子宫输卵管造影术或腹腔镜检查或两者均证实有输卵管积水。45例患者通过输卵管切除术或输卵管近端烧灼术对输卵管积水进行了手术治疗。在手术后3个月内进行体外受精-胚胎移植。比较妊娠率和着床率。

结果

与在体外受精周期前接受输卵管近端烧灼术的患者(分别为73%和36%)相比,输卵管积水患者每个周期的临床妊娠率和着床率显著降低(分别为14%和8%)。这些妊娠率和着床率与没有输卵管积水的输卵管因素不孕症患者(分别为53%和22%)以及接受输卵管切除术治疗的患者(分别为46%和24%)的妊娠率和着床率相当。

结论

输卵管近端烧灼术可有效逆转输卵管积水的不良影响。

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