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[一例结节病合并原发性甲状旁腺功能亢进症,是巧合还是因果关系?]

[A case of sarcoidosis with simultaneous primary hyperparathyroidism, coincedence or consequnce?].

作者信息

Hartmann F, Lehmann H

出版信息

Med Klin. 1975 May 16;70(20):904-8.

PMID:1094256
Abstract

We have reported of a case of generalised sarcoidosis with primary hyperparathyroidism. A pathogenetic relation between sarcoidosis associated with hypercalcemia and the development of parathyroid adenoma will be discussed and a causal connection will be proposed. According to our hypothesis every primary hyperparathyroidism could have developed from regulatory hyperfunction. This is illustrated by sarcoidosis with hypercalcemia and hypercalcuria. In this case a disturbance in vitamin D dependent calcium metabolism induces hyperplasia of the parathyroid which later leads to the development of a parathyroid adenoma. In addition a review of literature describing similar cases is given.

摘要

我们曾报道过一例全身性结节病合并原发性甲状旁腺功能亢进的病例。本文将讨论结节病伴高钙血症与甲状旁腺腺瘤发生之间的发病机制关系,并提出因果联系。根据我们的假设,每一例原发性甲状旁腺功能亢进可能都源于调节性功能亢进。结节病伴高钙血症和高钙尿症就说明了这一点。在这种情况下,维生素D依赖性钙代谢紊乱会导致甲状旁腺增生,进而发展为甲状旁腺腺瘤。此外,还对描述类似病例的文献进行了综述。

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