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[培养物生长早期厌氧诱导酵母线粒体降解]

[Degradation of yeast mitochondria induced by anaerobiosis at the early stages of growth of the culture].

作者信息

Luzikov V N, Raĭnia E I, Zubatov A S

出版信息

Tsitologiia. 1975 Mar;17(3):337-42.

PMID:1094652
Abstract

Prolonged anaerobiosis of Saccharomyces cerevisiae cells result in degenerative changes in mitochondria which can be revealed when measuring the enzyme activities of the respiratory chain in isolated organellas and by electron microscope examination of the cells. The sensitivity of yeast mitochondria to anaerosiosis alters as the culture growth. Mitochondria are especially labile during the early expotential growth phase. Possible reasons for and mechanism of degradation of mitochondria in vivo are discussed.

摘要

酿酒酵母细胞的长期无氧状态会导致线粒体发生退行性变化,这在测量分离细胞器中呼吸链的酶活性以及通过细胞的电子显微镜检查时可以显现出来。酵母线粒体对无氧状态的敏感性会随着培养物的生长而改变。线粒体在指数生长早期阶段尤其不稳定。本文讨论了体内线粒体降解的可能原因及机制。

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