Nordborg E
Department of Rheumatology, Sahlgrenska University Hospital, Göteborg, Sweden.
Clin Exp Rheumatol. 2000 Jul-Aug;18(4 Suppl 20):S15-7.
Giant cell arteritis (GCA) is reported world-wide. However, the incidence varies greatly in different geographic regions with the highest incidence rates from Scandinavian countries and North American populations of the same descent. The etiopathogenesis of GCA is incompletely understood. Although data on a positive correlation between the occurrence of infection and the onset of GCA as well as rhythmic fluctuations in disease incidence have been reported, no statistically significant periodicity has so far been found regarding the annual incidence of GCA. Seasonal variations may indicate a role of infection or other environmental factors in the pathogenesis of GCA.
巨细胞动脉炎（GCA）在全球范围内均有报道。然而，不同地理区域的发病率差异很大，斯堪的纳维亚国家以及具有相同血统的北美人群发病率最高。GCA的病因发病机制尚未完全明确。尽管有数据报道感染的发生与GCA的发病之间存在正相关以及疾病发病率的节律性波动，但迄今为止，关于GCA的年发病率尚未发现有统计学意义的周期性。季节变化可能表明感染或其他环境因素在GCA发病机制中起作用。
