Hamer M L, Robson M C, Krizek T J, Southwick W O
Ann Surg. 1975 Jun;181(6):819-22. doi: 10.1097/00000658-197506000-00010.
It is a biologic fact that all open wounds contain bacteria and remain contaminated with varying levels of bacteria until successful wound closure has been accomplished. The sine qua non in the management of the contaminated wound has been and remains adequate sharp debridement. In a standardized experimental model, three methods of irrigation were compared employing quantitative bacteriology of tissue to evaluate their effectiveness at decreasing bacterial levels and reducing wound infection. The pulsating jet lavate was found to be significantly better than gravity flow irrigation or wound irrigation with a bulb syringe. These data on tissue biopsies support previous reports using surface and wound exudate cultures.
所有开放性伤口都含有细菌,并且在伤口成功闭合之前一直被不同程度地污染,这是一个生物学事实。处理污染伤口的必要条件一直是且仍然是充分的锐性清创。在一个标准化的实验模型中,采用组织定量细菌学比较了三种冲洗方法,以评估它们在降低细菌水平和减少伤口感染方面的有效性。结果发现脉动喷射冲洗明显优于重力流冲洗或用球囊注射器进行伤口冲洗。这些组织活检数据支持了之前使用表面和伤口渗出物培养的报告。