Herzog R E
Arch Gynakol. 1975;218(1):25-30. doi: 10.1007/BF00672280.
Malignant tumors are determined by abnormal values of DNA as well as in its precursors. The cytophotometric analysis of smears allowed the determination of DNA of higher number of cells and therefore was presented as prescreening. But higher amounts of DNA caused by colpitis was reached too in this case. Therefore the presented research tried to limit points of malignancy by determination ofDNA, RNA, Histones, and Heterochromatin of cytologically classified cells. The discussion of results with literature pointed out, that this object is only reaching today by simultaneous determination of DNA and Heterochromatin of selected "atypical" cells.
恶性肿瘤由DNA及其前体的异常值决定。涂片的细胞光度分析能够测定更多细胞的DNA,因此被用作初步筛查。但在这种情况下,由阴道炎引起的DNA含量升高也会出现。因此,本研究试图通过测定细胞学分类细胞的DNA、RNA、组蛋白和异染色质来确定恶性程度。与文献的结果讨论指出,只有通过同时测定选定“非典型”细胞的DNA和异染色质,才能实现这一目标。