Kovác J, Mensa J
Kardiologická klinika, University of Leicester, Glenfieldská Vseobecná nemocnice, Velká Británie.
Vnitr Lek. 1999 Oct;45(10):610-3.
Sexual intercourse involves mild to medium severe physical exertion of the cardiovascular system. The risk of sudden death associated with sexual activity is very low, and so is the risk of developing infarction. In patients with pre-existing ischaemic heart disease sexual activity is safe in case of controlled angina with tolerance of a medium-grade load on examination on a treadmill. After acute myocardial infarction with a non-complicated course sexual activity can be resumed in a familiar environment with a familiar partner after about 10 days. In stabilized anginous patients sildenafil administration is safe assuming that the patient does not take long-acting nitrates and does not need frequent administration of short-term acting nitrates. It is important to avoid nitrates also in the treatment of acute ischaemic conditions in these patients. At present we do not possess adequate information on the clinical importance of influencing sildenafil elimination by competition with other substances excreted by the same route.
性交会使心血管系统产生轻度至中度的剧烈运动。与性活动相关的猝死风险非常低，发生梗死的风险也很低。对于已有缺血性心脏病的患者，在跑步机检查中能耐受中等负荷且心绞痛得到控制的情况下，性活动是安全的。急性心肌梗死病情无并发症的患者，大约10天后在熟悉的环境中和熟悉的伴侣在一起时可恢复性活动。对于病情稳定的心绞痛患者，假设患者不服用长效硝酸盐且不需要频繁服用短效硝酸盐，使用西地那非是安全的。在治疗这些患者的急性缺血性疾病时，避免使用硝酸盐也很重要。目前，我们尚无足够信息了解通过与经相同途径排泄的其他物质竞争来影响西地那非消除的临床重要性。
