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[Rare pulmonary complication in intravesical BCG treatment].

作者信息

Audigier C, Nesme P, Perol M, Guerin J C

机构信息

Service de Pneumologie, Hôpital de la Croix-Rousse, Lyon.

出版信息

Rev Mal Respir. 2000 Jun;17(3):679-81.

Abstract

We report a case of epithelioid granulomatous allergic lung disease in a patient given intra-bladder BCG therapy for treatment of a tumor. This uncommon complication is sometimes related to bacterial dissemination or to an immunoallegic reaction occurring from the third to eigth week after onset of the instillation. Clinically, the patient presents a flu-like syndrome. The standard chest X-ray followed by computed tomography, demonstrates the extension of the pulmonary lesions. Miliary dissemination is rarely reported (10 cases in the literature). Histological proof can be obtained from an endoscopic bronchial biopsy or a surgical specimen of the pulmonary parenchyma. Treatment is based on corticosteroid therapy in combination with antituberculosis antibiotics. Prognosis is generally good with treatment.

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