异常核作为先天性面瘫的一个病因。
The abnormal nucleus as a cause of congenital facial palsy.
作者信息
Jemec B, Grobbelaar A O, Harrison D H
机构信息
Department of Plastic Surgery, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK.
出版信息
Arch Dis Child. 2000 Sep;83(3):256-8. doi: 10.1136/adc.83.3.256.
BACKGROUND
Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive.
AIMS
To investigate the role of a neuroanatomical abnormality as a cause of unilateral CFP.
METHODS
Magnetic resonance imaging (MRI) scans were performed on 21 patients with unilateral CFP. Fifteen patients had unilateral CFP only; six suffered from syndromes which can include unilateral CFP.
RESULTS
Of the 15 patients with unilateral CFP only, four (27%) had an abnormal nucleus or an abnormal weighting of this area on the MRI scan, compared to one (17%) of the remaining six patients.
CONCLUSION
Developmental abnormalities of the facial nucleus itself constitute an important, and previously ignored, cause of monosymptomatic unilateral CFP.
背景
先天性面瘫（CFP）在临床上被定义为出生时即存在的面瘫。它会导致明显的面部畸形，并给患病儿童带来功能和情感问题。然而，大多数病例的病因仍然不明。
目的
研究神经解剖学异常作为单侧CFP病因的作用。
方法
对21例单侧CFP患者进行了磁共振成像（MRI）扫描。15例患者仅患有单侧CFP；6例患有可能包括单侧CFP的综合征。
结果
在仅患有单侧CFP的15例患者中，4例（27%）在MRI扫描中面神经核异常或该区域加权异常，而其余6例患者中有1例（17%）出现这种情况。
结论
面神经核本身的发育异常是单纯症状性单侧CFP的一个重要但此前被忽视的病因。
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