Hu F
J Invest Dermatol. 1979 Jul;73(1):70-9. doi: 10.1111/1523-1747.ep12532767.
Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age. Epidermal melanocytes, which normally divide only on demand or by stimulation, are classified as intermittent mitotic cells. During their development, lentigines and nevi of the skin show progressive ultrastructural and cytochemical changes similar to those in the choroidal cells, and thus may be considered as aging populations of skin melanocytes. These facts have led to the conclusion that choroidal melanocytes may be used advantageously as a model for studying changes in cells from maturation to senescence.
出生后动物眼睛的脉络膜黑素细胞被归类为有丝分裂后终末分化细胞。它们有特定的颗粒，即黑素小体，其在质量和数量上的变化与动物年龄的增长相关。表皮黑素细胞通常仅按需或受刺激时才分裂，被归类为间歇性有丝分裂细胞。在其发育过程中，皮肤的雀斑和痣表现出与脉络膜细胞相似的渐进性超微结构和细胞化学变化，因此可被视为皮肤黑素细胞的衰老群体。这些事实得出结论，脉络膜黑素细胞可有利地用作研究细胞从成熟到衰老变化的模型。
