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可触及的乳腺肿块:经皮影像引导下的粗针活检有作用吗?

Palpable breast masses: is there a role for percutaneous imaging-guided core biopsy?

作者信息

Liberman L, Ernberg L A, Heerdt A, Zakowski M F, Morris E A, LaTrenta L R, Abramson A F, Dershaw D D

机构信息

Department of Radiology, Breast Imaging Section, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021, USA.

出版信息

AJR Am J Roentgenol. 2000 Sep;175(3):779-87. doi: 10.2214/ajr.175.3.1750779.

DOI:10.2214/ajr.175.3.1750779
PMID:10954467
Abstract

OBJECTIVE

The purpose of this study was to evaluate percutaneous imaging-guided core biopsy in the assessment of selected palpable breast masses.

MATERIALS AND METHODS

Of 1388 consecutive breast lesions that had percutaneous imaging-guided core biopsy, 155 (11%) were palpable. Palpable masses referred for percutaneous imaging-guided core biopsy included lesions that were small, deep, mobile, vaguely palpable, or multiple. Biopsy guidance was sonography in 140 lesions (90%) and stereotaxis in 15 (10%). Surgical correlation or minimum of 2 years follow-up is available in 115 palpable masses in 107 women. Medical records, imaging studies, and histologic findings were reviewed.

RESULTS

Of 115 palpable breast masses, 98 (85%) were referred by surgeons to the radiology department for percutaneous imaging-guided core biopsy and 88 (77%) had percutaneous imaging-guided core biopsy on the day of initial evaluation at our institution. Percutaneous imaging-guided core biopsy spared additional diagnostic tissue sampling in 79 (74%) of 107 women, including 57 women with carcinoma and 22 women with benign findings. Percutaneous imaging-guided core biopsy did not spare additional tissue sampling in 28 women (26%), including 15 women in whom surgical biopsy was recommended on the basis of percutaneous biopsy findings and 13 women with benign (n = 7) or malignant (n = 6) percutaneous biopsy findings who chose to undergo diagnostic surgical biopsy.

CONCLUSION

Percutaneous imaging-guided core biopsy is useful in the evaluation of palpable breast masses that are small, deep, mobile, vaguely palpable, or multiple. In this study, percutaneous imaging-guided core biopsy spared additional diagnostic tissue sampling in 74% women with palpable breast masses.

摘要

目的

本研究旨在评估经皮影像引导下的粗针活检在选定可触及乳腺肿块评估中的应用。

材料与方法

在1388例接受经皮影像引导下粗针活检的连续乳腺病变中,155例(11%)为可触及病变。因经皮影像引导下粗针活检而转诊的可触及肿块包括小的、深在的、可活动的、触诊不明确的或多发的病变。140例病变(90%)的活检引导方式为超声,15例(10%)为立体定位。107名女性的115个可触及肿块有手术对照或至少2年的随访资料。对病历、影像检查和组织学结果进行了回顾。

结果

在115个可触及的乳腺肿块中,98个(85%)由外科医生转诊至放射科进行经皮影像引导下的粗针活检,88个(77%)在我院初次评估当天接受了经皮影像引导下的粗针活检。经皮影像引导下的粗针活检使107名女性中的79名(74%)无需进行额外的诊断性组织取样,其中包括57名患有癌症的女性和22名检查结果为良性的女性。经皮影像引导下的粗针活检未使28名女性(26%)免于额外的组织取样,其中包括15名根据经皮活检结果建议进行手术活检的女性,以及13名经皮活检结果为良性(n = 7)或恶性(n = 6)但选择接受诊断性手术活检的女性。

结论

经皮影像引导下的粗针活检对于评估小的、深在的、可活动的、触诊不明确的或多发的可触及乳腺肿块很有用。在本研究中,经皮影像引导下的粗针活检使74%的可触及乳腺肿块女性免于进行额外的诊断性组织取样。

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