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特发性小肠结肠淋巴细胞性静脉炎:缺血性结肠炎的罕见病因。

Idiopathic enterocolic lymphocytic phlebitis: a rare cause of ischemic colitis.

作者信息

Tuppy H, Haidenthaler A, Schandalik R, Oberhuber G

机构信息

Department of Pathology, Krankenhaus Wels, University of Vienna, Austria.

出版信息

Mod Pathol. 2000 Aug;13(8):897-9. doi: 10.1038/modpathol.3880160.

Abstract

We report on a 74-year-old female patient who was admitted to the hospital because of abdominal pain. She underwent a colonoscopy and a stenosing mass was found in the cecum. Histologic findings in the biopsy specimens were consistent with ischemic colitis. Due to clinical symptoms and the endoscopic and radiologic findings that roused the suspicion that the patient was suffering from a malignant tumor, a right hemicolectomy was performed. Histology of the resection specimen disclosed an inflammation of the veins. It was characterized by a predominantly lymphocytic infiltration of the vessels affecting the veins of the colonic wall and the mesentery. Furthermore, secondary thrombosis with focal venous occlusion was observed. The colon showed extensive ischemic colitis with focal transmural coagulation necrosis. The disease was considered to be idiopathic lymphocytic phlebitis, which is a rare disease of unknown origin. Our patient is well and alive after more than 1 year, supporting the notion that the disease shows a benign course after surgery.

摘要

我们报告了一名74岁的女性患者,她因腹痛入院。她接受了结肠镜检查,在盲肠发现了一个狭窄性肿块。活检标本的组织学结果与缺血性结肠炎一致。由于临床症状以及内镜和影像学检查结果引发了对患者患有恶性肿瘤的怀疑,遂进行了右半结肠切除术。切除标本的组织学检查显示静脉炎症。其特征是血管主要为淋巴细胞浸润,累及结肠壁和肠系膜的静脉。此外,还观察到继发性血栓形成伴局灶性静脉闭塞。结肠显示广泛的缺血性结肠炎伴局灶性透壁性凝固性坏死。该疾病被认为是特发性淋巴细胞性静脉炎,这是一种病因不明的罕见疾病。我们的患者在1年多后情况良好且存活,这支持了该疾病术后呈良性病程的观点。

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