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伪装成盲肠恶性狭窄的肠结肠淋巴细胞性静脉炎:一例报告及文献复习

Enterocolic Lymphocytic Phlebitis Masquerading as a Malignant Stricture in the Caecum: A Case Report and Literature Review.

作者信息

Agrawal Dakshita, Agrawal Rakshita, Narayanasamy Sangara, Ramasamy Sadhasivam, Mohamedahmed Ali Yasen, Thomas Pradeep, Husain Najam

机构信息

General Surgery, Queen's Hospital Burton, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.

出版信息

Cureus. 2024 Oct 30;16(10):e72699. doi: 10.7759/cureus.72699. eCollection 2024 Oct.

DOI:10.7759/cureus.72699
PMID:39483553
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11527501/
Abstract

Enterocolic lymphocytic phlebitis (ELP) is an idiopathic form of venous inflammation that is limited to the gastrointestinal tract. It is characterised by inflammation of the veins with no involvement of the arteries. Usually, it presents with gastrointestinal symptoms such as abdominal pain, and imaging may suggest malignancy. The reported case is a 56-year-old female presented with rectal bleeding, abdominal pain and diarrhoea. All blood test results were normal; however, she had an elevated C-reactive protein (CRP) level. Computed tomography colonography showed caecal wall thickening, suggesting caecal malignancy. Following a multidisciplinary discussion, the patient had a right hemicolectomy, and the histology showed no malignancy and typical features of ELP. This is a rare idiopathic form of venous inflammation localised to the gastrointestinal tract, which can occasionally present similarly to bowel malignancy. ELP most commonly presents with abdominal pain, followed by hematochezia and diarrhaea. The duration of symptoms varies widely, from hours to a year. Diagnosis is usually confirmed by histopathological assessment. We present this case and literature review considering its rarity, which adds to the literature on this condition.

摘要

小肠结肠淋巴细胞性静脉炎(ELP)是一种局限于胃肠道的特发性静脉炎症形式。其特征是静脉炎症,不累及动脉。通常,它表现为腹痛等胃肠道症状,影像学检查可能提示恶性肿瘤。报告的病例是一名56岁女性,表现为直肠出血、腹痛和腹泻。所有血液检查结果均正常;然而,她的C反应蛋白(CRP)水平升高。计算机断层结肠成像显示盲肠壁增厚,提示盲肠恶性肿瘤。经过多学科讨论,患者接受了右半结肠切除术,组织学检查显示无恶性肿瘤,且具有ELP的典型特征。这是一种罕见的局限于胃肠道的特发性静脉炎症形式,偶尔可能表现得与肠道恶性肿瘤相似。ELP最常见的表现是腹痛,其次是便血和腹泻。症状持续时间差异很大,从数小时到一年不等。诊断通常通过组织病理学评估来确认。鉴于其罕见性,我们呈现此病例并进行文献综述,这为关于这种疾病的文献增添了内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/945b9fdd7cbb/cureus-0016-00000072699-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/2299b5ab5a48/cureus-0016-00000072699-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/836cb63e4ee3/cureus-0016-00000072699-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/945b9fdd7cbb/cureus-0016-00000072699-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/2299b5ab5a48/cureus-0016-00000072699-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/836cb63e4ee3/cureus-0016-00000072699-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11527501/945b9fdd7cbb/cureus-0016-00000072699-i03.jpg

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本文引用的文献

1
Enterocolic phlebitis: a rare cause of bowel ischemia and review of the literature.小肠结肠静脉炎:肠道缺血的罕见病因及文献综述
Gastroenterol Rep (Oxf). 2023 Feb 1;11:goad002. doi: 10.1093/gastro/goad002. eCollection 2023.
2
Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents.术前使用生物制剂和免疫抑制剂治疗的结肠小肠淋巴细胞性静脉炎
Case Rep Pathol. 2022 Mar 7;2022:5120607. doi: 10.1155/2022/5120607. eCollection 2022.
3
Enterocolic lymphocytic phlebitis: a rare pathology in children.
回肠血管淋巴细胞性静脉炎:儿童罕见疾病。
BMJ Case Rep. 2021 Aug 23;14(8):e243826. doi: 10.1136/bcr-2021-243826.
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Not in the Same Vein: Inflammatory Bowel Disease, Malignancy, and Enterocolic Lymphocytic Phlebitis.
Dig Dis Sci. 2021 Feb;66(2):413-418. doi: 10.1007/s10620-020-06425-w.
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Enterocolic lymphocytic phlebitis with marked myointimal hyperplasia and perivenous concentric fibrosis.回肠血管淋巴细胞性静脉炎,伴显著的血管内膜增生和静脉周围同心性纤维化为特征。
Cardiovasc Pathol. 2019 May-Jun;40:68-71. doi: 10.1016/j.carpath.2019.02.006. Epub 2019 Mar 6.
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Enterocolic Lymphocytic Phlebitis: A Mimicking Entity.小肠结肠淋巴细胞性静脉炎:一种易混淆的病症。
Int J Surg Pathol. 2019 Aug;27(5):526. doi: 10.1177/1066896918809511. Epub 2018 Oct 29.
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Enterocolic lymphocytic phlebitis as a newly recognized manifestation of IgG4-related disease.
Int J Surg Pathol. 2015 Apr;23(2):165-9. doi: 10.1177/1066896914539549. Epub 2014 Jun 17.
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Enterocolic lymphocytic phlebitis: an oncologic surgical resection without a preoperative pathologic diagnosis.小肠结肠淋巴细胞性静脉炎:一例未经术前病理诊断的肿瘤外科切除术。
J Surg Case Rep. 2014 May 15;2014(5):rju037. doi: 10.1093/jscr/rju037.
9
Enterocolic lymphocytic phlebitis preceding the development of inflammatory bowel disease: report of a case.炎症性肠病发生前的结肠小肠淋巴细胞性静脉炎:一例报告
Rev Esp Enferm Dig. 2013 Oct;105(9):571-2. doi: 10.4321/s1130-01082013000900016.
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Enterocolic lymphocytic phlebitis: an unusual cause of abdominal complaints.
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