Development of an efficient intermediate, alpha-[2-(trimethylsilyl)ethoxy]-2-N- [2-(trimethylsilyl)ethoxycarbonyl]folic acid, for the synthesis of folate (gamma)-conjugates, and its application to the synthesis of folate-nucleoside conjugates.
作者信息
Nomura M, Shuto S, Matsuda A
机构信息
Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
出版信息
J Org Chem. 2000 Aug 11;65(16):5016-21. doi: 10.1021/jo000132a.
PMID:10956487
Abstract
摘要
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