Lee D, Choi Y K, Kim M J
Department of Chemistry, Division of Molecular and Life Science, Pohang University of Science and Technology, San 31 Hyojadong, Pohang, Kyungbuk 790-784, Korea.
Org Lett. 2000 Aug 10;2(16):2553-5. doi: 10.1021/ol0062897.
The substrate matching strategy is described as a new approach for effectively enhancing the lipase enantioselectivity in organic solvent. In the lipase-catalyzed transesterifications of 3a-c, higher enantioselectivities have been achieved using 1a-c, respectively, as the structurally matched acyl donors.
底物匹配策略被描述为一种在有机溶剂中有效提高脂肪酶对映体选择性的新方法。在脂肪酶催化的3a - c的酯交换反应中，分别使用1a - c作为结构匹配的酰基供体，已实现了更高的对映体选择性。
