氯霉素对λ调控突变体溶原化的刺激作用。
Chloramphenicol stimulation of lysogeny by lambda regulatory mutants.
作者信息
Kudrna R, Edlin G
出版信息
J Virol. 1975 Jun;15(6):1504-6. doi: 10.1128/JVI.15.6.1504-1506.1975.
Abstract
Inhibition of protein synthesis in Escherichia coli by amino acid starvation or chloramphenicol addition increases the frequency of lysogeny by lambda phage two- to fourfold. Lambda cIII mutants, which normally lysogenize at very low frequencies, lysogenize at very high frequencies in the presence of chloramphenicol.
摘要
通过氨基酸饥饿或添加氯霉素抑制大肠杆菌中的蛋白质合成，可使λ噬菌体的溶原化频率提高两到四倍。通常以极低频率溶原化的λ cIII突变体，在氯霉素存在的情况下以非常高的频率溶原化。
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本文引用的文献
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