Khananashvili M M
Zh Nevrol Psikhiatr Im S S Korsakova. 2000;100(7):18-22.
The clinical features and the course of seasonal depressions in endogenous mental diseases were studied with psychopathological and follow-up methods. The seasonal depressions in 50 patients were developed in the psychopathological structure of manic-depressive psychosis (22 patients), schizoaffective psychosis (23) and schizoaffective variant of schizophrenia (5). There were found the considerable differences in the characteristics of seasonal depressions in the indicated endogenous psychoses. The was established that spring summer depressions had more favorable prognostic meaning in comparison with fall-winter depressions. There was shown that changes or disappearance of the seasonal rhythm of depression's development was prognostic unfavourable sign and pointed to the change to the worse of disease.
采用精神病理学和随访方法对内源性精神疾病中季节性抑郁症的临床特征及病程进行了研究。50例患者的季节性抑郁症发生于躁狂抑郁症（22例）、分裂情感性精神病（23例）和精神分裂症的分裂情感性变体（5例）的精神病理结构中。结果发现，上述内源性精神病中季节性抑郁症的特征存在显著差异。已证实，与秋冬抑郁症相比，春夏抑郁症具有更有利的预后意义。结果表明，抑郁症发作季节性节律的改变或消失是预后不良的标志，提示病情恶化。
