Tubiana M, Richard J M, Malaise E
Laryngoscope. 1975 Jun;85(6):1039-52. doi: 10.1288/00005537-197506000-00012.
After a brief survey of the factors of clinical tumor radioresistance the available data on the growth rate and on the kinetics of cell proliferation of U.R.D.T. tumors are reviewed. The growth fraction and the cell turnover rate appear to be similar in U.R.D.T. tumors and in other squamous cell carcinomas. These two parameters are correlated with clinical tumor radiosensitivity and chemosensitivity. The possible value of tailoring fractionation and drug administration to the biological characteristics of the tumor is discussed.
在简要概述临床肿瘤放射抗性因素之后，回顾了关于泌尿生殖系统移行细胞肿瘤（U.R.D.T.）生长速率和细胞增殖动力学的现有数据。U.R.D.T.肿瘤与其他鳞状细胞癌的生长分数和细胞更新率似乎相似。这两个参数与临床肿瘤放射敏感性和化学敏感性相关。讨论了根据肿瘤生物学特性调整分割放疗和药物给药的可能价值。
