Peters W, Piotrowska H, Serafin B, Urbański T
Pol J Pharmacol Pharm. 1975 May-Jun;27(3):289-95.
The molecule of RC 12 which was found previously to exhibit antimalarial activity has been modified, by replacing groups in positions 1 and 2 by NHAr, S-Ar, NO2, sulfonamido and other substituents. The new derivatives (Table 1) were tested for toxicity and antimalarial activity agains Plasmodium berghei in mice (Table 2).
先前发现具有抗疟活性的RC 12分子已被修饰，即将1位和2位的基团替换为NHAr、S-Ar、NO2、磺酰胺基和其他取代基。对新衍生物（表1）进行了毒性测试，并针对小鼠体内的伯氏疟原虫测试了其抗疟活性（表2）。
