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萝芙木根片中指定黏合剂的评估。

Evaluation of named binders in Rauwolfia vomitoria root tablets.

作者信息

Onunkwo G C

机构信息

Department of Pharmaceutical Technology and Industrial Pharmacy-Faculty of Pharmaceutical Sciences-University of Nigeria, Nsukka, Nigeria.

出版信息

Boll Chim Farm. 2000 May-Jun;139(3):132-9.

Abstract

Some physical properties of Rauwolfia vomitoria root tablets were studied. Tablet characteristics studied were: weight uniformity, tensile strength, friability, disintegration time and content uniformity. Tablet property varied depending on the type and concentration of the binder. The tablets had type and concentration of the binder. The tablets had acceptable hardness and friability profiles. Although tablets containing 150 mg R. vomitoria root had lower tensile strength values. All the tablets passed the B.P. disintegration time test of 15 min. Moreover tablets containing 150 mg R. vomitoria root disintegrated under 1 min. at 4% w/w binder concentration.

摘要

对催吐萝芙木根片的一些物理性质进行了研究。所研究的片剂特性包括:重量差异、抗张强度、脆碎度、崩解时间和含量均匀度。片剂性质因粘合剂的类型和浓度而异。片剂具有粘合剂的类型和浓度。片剂具有可接受的硬度和脆碎度曲线。尽管含有150mg催吐萝芙木根的片剂抗张强度值较低。所有片剂均通过了英国药典15分钟的崩解时间测试。此外,含有150mg催吐萝芙木根的片剂在4%w/w粘合剂浓度下1分钟内崩解。

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