Duclos J
Servicio de Medicina, Hospital Naval de Viña del Mar.
Rev Med Chil. 2000 Feb;128(2):211-2.
A 35 years old male is presented. Eight months after receiving a renal allograft his hypertension worsened and his packed red cell volume raised to 53.7% Enalapril was started and a 500 ml phlebotomy was performed. In three occasions packed red cell volumes decreased excessively and enalapril was discontinued. Finally, the drug was replaced with losartan, normalizing blood pressure values and stabilizing packed red cell volumes. This case illustrates the different reductions in packed red cell volumes induced by enalapril and losartan. These differences could have a therapeutic relevance.
一名35岁男性患者前来就诊。接受同种异体肾移植八个月后，他的高血压病情加重，红细胞压积升至53.7%。开始使用依那普利，并进行了500毫升静脉放血治疗。有三次红细胞压积过度降低，依那普利停药。最后，该药物被氯沙坦取代，血压值恢复正常，红细胞压积稳定。该病例说明了依那普利和氯沙坦引起的红细胞压积的不同降低情况。这些差异可能具有治疗意义。
