Mobacken H, Holst R, Wengström C, Holm S E
Scand J Infect Dis. 1975;7(1):39-44. doi: 10.3109/inf.1975.7.issue-1.07.
200 patients with primary impetigo were studied. Staphylococcus aureus was the only organism isolated in 72.5%, beta-hemolytic streptococci, group A, in 10%, and both pathogens in 15%. 17 of the 50 streptococcal isolates were typed serologically; 11 of these belonged to potentially nephritogenic types. A majority of these cases had identical strains in the nose and throat. Hence, the primary source of skin streptococcal in this study may be the nasopharynx. Uncomplicated cases were treated with topical antibiotics, and oral antibiotics were added in 22 cases with extensive lesions, fever or a concurrent throat infection. None of the 200 patients developed acute glomerulonephritis and urinary analyses were normal at follow-up after 3 weeks.
对200例原发性脓疱病患者进行了研究。72.5%的患者仅分离出金黄色葡萄球菌,10%的患者分离出A组β溶血性链球菌,15%的患者两种病原体都有。50株链球菌分离株中有17株进行了血清学分型;其中11株属于潜在致肾炎型。这些病例中的大多数在鼻腔和咽喉部有相同菌株。因此,本研究中皮肤链球菌的主要来源可能是鼻咽部。单纯病例采用局部抗生素治疗,22例病变广泛、发热或并发咽喉感染的患者加用了口服抗生素。200例患者均未发生急性肾小球肾炎,3周后随访时尿液分析正常。