Cvjetković-Bosnjak M, Knezević A, Soldatović-Stajić B
Institut za neurologiju, psihijatriju i mentalno zdravlje, Klinicki centar, Novi Sad Medicinski fakultet, Novi Sad.
Med Pregl. 2000 Mar-Apr;53(3-4):184-6.
Depression is a common problem in old age, especially among those with various medical illnesses. Aging brings about numerous losses that might lead to depression: loss of health, loved ones and social roles. Some of older persons develop depression. Depression in old age is a serious illness. The suicide rate among older persons is very high. Approximately 90% of elderly people who commit suicide suffer from depression. Adequate treatment of depression in late life includes reducing and resolving depressive symptoms, preventing its relapse and reoccurrence, improving quality of life, and reducing mortality and healthcare costs.
32 female inpatients were examined. All patients suffered from depressive disorder (middle, according to International Classification of Diseases (ICD-X). Only patients without cognitive impairment were included in the study, according to Mini-Mental State Examination. Hamilton Rating Scale for Depression was used as primary measure of efficacy. Patients were evaluated for efficacy weekly. For statistical analysis t test was used.
Depressive disorders are more severe among older patients, with greater suicidal risk, anxiety and psychomotor agitation. Patients treated with moclobemide show quicker remission of depressive symptoms compared to patients who were treated with mianserin.
Depressive disorders among older patient are very serious illnesses, but with adequate therapy, symptoms can disappear, and there is no difference between remission in depression among older and younger patients.
抑郁症是老年人中的常见问题，尤其是在患有各种疾病的人群中。衰老会带来许多可能导致抑郁的损失：健康、亲人及社会角色的丧失。一些老年人会患上抑郁症。老年抑郁症是一种严重疾病。老年人的自杀率非常高。约90%的自杀老年人患有抑郁症。对晚年抑郁症的充分治疗包括减轻和消除抑郁症状、预防复发和再发、提高生活质量以及降低死亡率和医疗成本。
对32名女性住院患者进行了检查。所有患者均患有抑郁症（根据国际疾病分类（ICD-X）为中度）。根据简易精神状态检查表，仅纳入无认知障碍的患者。汉密尔顿抑郁量表用作疗效的主要衡量指标。每周对患者的疗效进行评估。采用t检验进行统计分析。
老年患者的抑郁症更为严重，自杀风险、焦虑和精神运动性激越更高。与接受米安色林治疗的患者相比，接受吗氯贝胺治疗的患者抑郁症状缓解更快。
老年患者的抑郁症是非常严重的疾病，但通过适当治疗，症状可以消失，老年患者与年轻患者抑郁症的缓解情况并无差异。
