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[腭咽麻痹:一例报告]

[Velopharyngeal palsy: a case report].

作者信息

Mon Y, Nakamura N

机构信息

Department of Neurology, Kyoto-min-iren Dai-ni Chuo Hospital.

出版信息

Rinsho Shinkeigaku. 2000 Apr;40(4):364-6.

PMID:10967654
Abstract

Here we present a case of velopharyngeal palsy. An 18-year-old man had hyperemia in his left conjunctivum. One or two weeks later he experienced nasal speech and difficulty in swallowing. General physical examination was normal. The only abnormal neurological finding was palato-pharyngeal paralysis on the right side. MRI of the head and neck had no abnormalities. Acute and convalescent sera showed no rise in viral antibody titer. CSF examination was normal except for the increased IgG% and IgG.albumin index. Treatment consisted of glycerol and steroid, and his symptom improved within two or three weeks. We think immunological mechanism is important because CSF examination showed increased IgG% and IgG.albumin index in our case. Acquired and isolated velopharyngeal palsy is uncommon. Only 26 cases have been reported so far. This is the first case in Japan. The disease has some characteristics. This occurs in childhood and adolescence. Onset is sudden, consisting in rhinolalia and dysphagia. On examination there is asymmetry of the pharynx and deviation of the uvula contralateral to the affected side. There is no other neurological abnormalities. Complete spontaneous recovery is usual. In some cases viral infection is the cause, but in most cases the cause is unknown. In contrast, the disease with both acquired velopharyngeal palsy and vocal cord palsy is relatively common. This occurs in the middle aged or elderly people. In addition to dysphagia and hoarse voice, this disease often accompanies neurological abnormalities such as other cranial nerve palsy and meningitis, fever, and pain in the pharyngeal region. In most cases viral infection is the cause.

摘要

在此,我们呈现一例腭咽麻痹病例。一名18岁男性左侧结膜充血。一两周后,他出现鼻音和吞咽困难。全身体格检查正常。唯一异常的神经学表现是右侧腭咽麻痹。头颈部MRI未见异常。急性期和恢复期血清病毒抗体滴度均未升高。脑脊液检查除IgG%和IgG.白蛋白指数升高外均正常。治疗包括使用甘油和类固醇,其症状在两到三周内有所改善。我们认为免疫机制很重要,因为在我们的病例中脑脊液检查显示IgG%和IgG.白蛋白指数升高。获得性孤立性腭咽麻痹并不常见。迄今为止仅报道了26例。这是日本的首例病例。该疾病具有一些特点。它发生于儿童期和青少年期。起病突然,表现为鼻音和吞咽困难。检查可见咽部不对称,悬雍垂偏向患侧对侧。无其他神经学异常。通常可完全自发恢复。在某些情况下,病毒感染是病因,但在大多数情况下病因不明。相比之下,同时伴有获得性腭咽麻痹和声带麻痹的疾病相对常见。它发生于中年或老年人。除吞咽困难和声音嘶哑外,该疾病常伴有其他颅神经麻痹、脑膜炎、发热及咽部疼痛等神经学异常。在大多数情况下,病毒感染是病因。

相似文献

1
[Velopharyngeal palsy: a case report].[腭咽麻痹:一例报告]
Rinsho Shinkeigaku. 2000 Apr;40(4):364-6.
2
[A case of Avellis' syndrome with ipsilateral central facial palsy due to a small medullary infarction].[一例因延髓小梗死导致同侧中枢性面瘫的阿韦利斯综合征病例]
Rinsho Shinkeigaku. 2000 Apr;40(4):409-11.
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[A case of unilateral VIIIth, IXth and Xth cranial nerve involvement with herpes zoster].[1例带状疱疹累及单侧第Ⅷ、Ⅸ和Ⅹ颅神经]
Rinsho Shinkeigaku. 1990 Apr;30(4):413-5.
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[Unilateral isolated paralysis of the soft palate: a case report and a review of the literature].[软腭单侧孤立性麻痹:一例报告及文献综述]
Rev Neurol. 2003;36(4):337-9.
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[Internal ophthalmoplegia in acute oropharyngeal palsy with anti-GQ1b and anti-GT1a IgG antibodies].[伴有抗GQ1b和抗GT1a IgG抗体的急性口咽性麻痹中的眼内肌麻痹]
No To Shinkei. 2005 Jun;57(6):523-6.
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[Avellis syndrome in systemic rheumatoid vasculitis].[系统性类风湿性血管炎中的阿韦利斯综合征]
Rinsho Shinkeigaku. 1995 Oct;35(10):1155-9.
7
[A case of isolated vagus nerve palsy with herpes zoster].
Rinsho Shinkeigaku. 1994 Sep;34(9):928-9.
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[A case of Miller Fisher syndrome with pharyngeal palsy as an initial symptom].以咽麻痹为首发症状的米勒-费希尔综合征1例
No To Shinkei. 2001 Mar;53(3):275-8.
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[A case of supranuclear hypoglossal nerve palsy with Avellis' syndrome due to a medullary infarction].[一例因延髓梗死导致核上性舌下神经麻痹伴阿韦利斯综合征的病例]
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[A 65-year-old man with rigid-bradykinetic parkinsonism, vertical gaze palsy, difficulty of eye-lid opening, and marked pseudo-bulbar palsy].一名65岁男性,患有强直-少动型帕金森症、垂直凝视麻痹、眼睑睁开困难及明显的假性球麻痹。
No To Shinkei. 2005 Jan;57(1):73-86.

引用本文的文献

1
Acute idiopathic velopharyngeal insufficiency.急性特发性软腭闭合不全。
Pan Afr Med J. 2020 Dec 21;37:359. doi: 10.11604/pamj.2020.37.359.26072. eCollection 2020.
2
Acute isolated velopharyngeal insufficiency in children: case report and systematic review of the literature.儿童急性孤立性软腭功能不全:病例报告和文献系统回顾。
Eur Arch Otorhinolaryngol. 2013 Jul;270(7):1975-80. doi: 10.1007/s00405-012-2215-0. Epub 2012 Oct 9.