Mohammed R, Goh K L, Wong N W
Department of Medicine, University Hospital, Kuala Lumpur.
Med J Malaysia. 1996 Mar;51(1):99-102.
Primary biliary cirrhosis is an uncommon disease amongst Malaysians. Over a 12-year period, between 1979 and 1991, only seven patients with clinical, biochemical and histologic evidence of primary biliary cirrhosis were identified in University Hospital Kuala Lumpur. All were Chinese females between the ages of 30 to 55 years. The presenting complaint was pruritus in 5 patients. All except one patient was jaundiced when the diagnosis was made. These patients were followed up from 1 to 11 years. Three deaths were reported, one from massive hemetemesis and two from liver failure.
原发性胆汁性肝硬化在马来西亚人中是一种罕见疾病。在1979年至1991年的12年期间,吉隆坡大学医院仅确诊了7例有原发性胆汁性肝硬化临床、生化及组织学证据的患者。所有患者均为30至55岁的中国女性。5例患者的主要症状为瘙痒。确诊时,除1例患者外,其余患者均有黄疸症状。这些患者接受了1至11年的随访。报告了3例死亡病例,1例死于大量呕血,2例死于肝功能衰竭。