Bromage P R
Br J Anaesth. 1975 Feb;47 suppl:199-211.
The factors governing the spread and site of action of local anaesthetics in the extradural space are discussed. Local anaesthetic drugs injected into the extradural space may cause nerve blocks at three possible sites: (a) On the spinal nerves in the paravertebral space. This probably occurs only in young subjects. (b) On the spinal nerves intradurally. This is probably the essential site of blockade. (c) On the spinal cord.
讨论了影响局部麻醉药在硬膜外间隙扩散及作用部位的因素。注入硬膜外间隙的局部麻醉药可能在三个部位导致神经阻滞:(a)在椎旁间隙的脊神经上。这可能仅发生在年轻受试者中。(b)在硬膜内的脊神经上。这可能是阻滞的主要部位。(c)在脊髓上。