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硬膜外镇痛的作用机制。

Mechanism of action of extradural analgesia.

作者信息

Bromage P R

出版信息

Br J Anaesth. 1975 Feb;47 suppl:199-211.

PMID:1096918
Abstract

The factors governing the spread and site of action of local anaesthetics in the extradural space are discussed. Local anaesthetic drugs injected into the extradural space may cause nerve blocks at three possible sites: (a) On the spinal nerves in the paravertebral space. This probably occurs only in young subjects. (b) On the spinal nerves intradurally. This is probably the essential site of blockade. (c) On the spinal cord.

摘要

讨论了影响局部麻醉药在硬膜外间隙扩散及作用部位的因素。注入硬膜外间隙的局部麻醉药可能在三个部位导致神经阻滞:(a)在椎旁间隙的脊神经上。这可能仅发生在年轻受试者中。(b)在硬膜内的脊神经上。这可能是阻滞的主要部位。(c)在脊髓上。

相似文献

1
Mechanism of action of extradural analgesia.硬膜外镇痛的作用机制。
Br J Anaesth. 1975 Feb;47 suppl:199-211.
2
The physiology and pharmacology of epidural blockade.硬膜外阻滞的生理学与药理学
Clin Anesth. 1969;2:45-61.
3
Extradural anaesthesia: choice of local anaesthetic agents.硬膜外麻醉:局部麻醉药的选择
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Clinical observations suggesting a changing site of action during induction and recession of spinal and epidural anesthesia.临床观察表明,在脊髓麻醉和硬膜外麻醉诱导及消退过程中作用部位发生变化。
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Ropivacaine produces sensory blockade in the lumbar sacral region more frequently than mepivacaine in lower thoracic epidural anesthesia.在胸段硬膜外麻醉中,罗哌卡因比甲哌卡因更常引起腰骶部感觉阻滞。
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Local anesthesia. 2.局部麻醉。2.
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[Relevance of nerve blocks in treating and diagnosing low back pain--is the quality decisive?].[神经阻滞在治疗和诊断腰背痛中的相关性——质量起决定性作用吗?]
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Local anesthetics.局部麻醉药
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Spinal and extradural analgesia-anesthesia for parturition.分娩的脊髓和硬膜外镇痛-麻醉
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