Fink-Puches R, Smolle J, Beham A, Kerl H, Soyer H P
Universitätsklinik für Dermatologie und Venerologie, Graz.
Hautarzt. 2000 Jul;51(7):479-85. doi: 10.1007/s001050051157.
Angiosarcomas of the skin arise almost exclusively in the following clinical settings: 1. the face and scalp, usually in elderly individuals, 2. lymphedematous regions (lymphedema-associated angiosarcomas), and 3. skin that has been previously irradiated (post-radiation angiosarcomas). Clinical and histopathologic diagnosis of angiosarcoma is difficult often resulting in great delay that obviates against early and possibly successful treatment of these very aggressive neoplasms. Diagnostic problems are described, and prognostic factors as well as the effect of different forms of treatment on the outcome are discussed.
PATIENTS/METHODS: Retrospective study of 11 patients with cutaneous angiosarcomas. Clinical presentation, histopathology, therapy and survival time are analysed.
Only 1 of 11 cases cutaneous angiosarcoma was clinically identified. Survival time was 1-24 months. Three patients who received radical surgery have not developed metastases and are still alive.
Clinical and histopathologic diagnosis of cutaneous angiosarcomas is often very difficult. Prognosis is very bad; radical surgery seems to be the best therapeutical option.
皮肤血管肉瘤几乎仅发生于以下临床情况：1. 面部和头皮，通常见于老年人；2. 淋巴水肿区域（淋巴水肿相关血管肉瘤）；3. 先前接受过放疗的皮肤（放疗后血管肉瘤）。血管肉瘤的临床和组织病理学诊断困难，常导致严重延误，不利于对这些极具侵袭性的肿瘤进行早期且可能成功的治疗。文中描述了诊断问题，并讨论了预后因素以及不同治疗方式对预后的影响。
患者/方法：对11例皮肤血管肉瘤患者进行回顾性研究。分析临床表现、组织病理学、治疗方法及生存时间。
11例皮肤血管肉瘤患者中仅1例在临床上得到确诊。生存时间为1至24个月。3例接受根治性手术的患者未发生转移，仍存活。
皮肤血管肉瘤的临床和组织病理学诊断通常非常困难。预后很差；根治性手术似乎是最佳治疗选择。
