• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

胎儿胸腺对胎儿肝细胞的增强作用，可促进小鼠同种异体辐射嵌合体从辐射损伤中恢复，或者说一点点胸腺就能发挥很大的作用。

Potentiating effect of fetal thymus on fetal liver cells for the promotion of recovery from the radiation injury in murine allogenic radiation chimeras or a little bit of thymus goes a long, long way.

作者信息

Bortin M M, Rimm A A, Saltzstein E C

出版信息

Birth Defects Orig Artic Ser. 1975;11(1):544-8.

PMID:1096994
Abstract

Lethally irradiated CBA (H-2k) mice were treated with small numbers of liver cells from strain-A (H-2a) fetal donors. Recovery from the radiation injury was dependent upon the dose of liver cells administered. Giving very small numbers of fetal thymus cells, in addition to liver cells, had a highly significant and salutary effect on survival. The results suggest that clinical transplantation of liver cells from a single fetus might succeed if thymus cells are added.

摘要

用来自A品系（H-2a）胎儿供体的少量肝细胞对受到致死剂量照射的CBA（H-2k）小鼠进行治疗。辐射损伤的恢复取决于所给予的肝细胞剂量。除肝细胞外，给予极少量的胎儿胸腺细胞对小鼠存活有非常显著的有益影响。结果表明，如果添加胸腺细胞，单个胎儿的肝细胞临床移植可能会成功。

相似文献

1
Potentiating effect of fetal thymus on fetal liver cells for the promotion of recovery from the radiation injury in murine allogenic radiation chimeras or a little bit of thymus goes a long, long way.胎儿胸腺对胎儿肝细胞的增强作用，可促进小鼠同种异体辐射嵌合体从辐射损伤中恢复，或者说一点点胸腺就能发挥很大的作用。
Birth Defects Orig Artic Ser. 1975;11(1):544-8.
2
Long lived canine allogeneic radiation chimera produced with combined fetal liver and thymus cells.用胎儿肝脏和胸腺细胞联合产生的长寿犬同种异体辐射嵌合体。
Transplantation. 1974 Nov;18(5):461-3.
3
Fetal liver cell transplantation in various murine models.
Bone Marrow Transplant. 1992;9 Suppl 1:77-82.
4
Promotion of fetal liver cell engraftment in irradiated mice by activated T lymphocytes.活化T淋巴细胞促进受辐照小鼠的胎肝细胞植入
Bone Marrow Transplant. 1993 Oct;12(4):307-14.
5
Ia-positive nonlymphoid cells and T cell development in murine fetal thymus organ cultures: monoclonal anti-Ia antibodies inhibit the development of T cells.Ia阳性非淋巴细胞与小鼠胚胎胸腺器官培养中的T细胞发育：单克隆抗Ia抗体抑制T细胞发育。
J Immunol. 1986 Jan;136(2):430-9.
6
Long-term survival of murine allogeneic bone marrow chimeras: effect of anti-lymphocyte serum and bone marrow dose.小鼠同种异体骨髓嵌合体的长期存活：抗淋巴细胞血清和骨髓剂量的影响。
J Immunol. 1981 Feb;126(2):428-32.
7
Effect of T cell supplementation to fetal liver cells transplanted into isogeneic mice.向移植到同基因小鼠体内的胎肝细胞补充T细胞的效果。
Transplantation. 1988 Nov;46(5):779-82.
8
Transplantation of newborn thymus plus hematopoietic stem cells can rescue supralethally irradiated mice.移植新生胸腺加造血干细胞可挽救受到超致死剂量照射的小鼠。
Bone Marrow Transplant. 2008 Apr;41(7):659-66. doi: 10.1038/sj.bmt.1705957. Epub 2008 Jan 7.
9
SCID-hu mice as a model to study tolerance after fetal stem cell transplantation.严重联合免疫缺陷-人源化小鼠作为研究胎儿干细胞移植后耐受性的模型。
Bone Marrow Transplant. 1992;9 Suppl 1:83-4.
10
Effect of ionizing radiation on thymic epithelial cell function. I. Radiation-spared thymic epithelial grafts expedite the recovery of T cell function in lethally irradiated and fetal liver reconstituted mice.电离辐射对胸腺上皮细胞功能的影响。I. 辐射保留的胸腺上皮移植加速致死性照射并经胎肝重建的小鼠的T细胞功能恢复。
J Immunol. 1988 Jan 1;140(1):21-9.