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游离大网膜转移治疗下颌骨放射性骨坏死

Free omental transfer for osteoradionecrosis of the mandible.

作者信息

Kobayashi W, Kobayashi M, Nakayama K, Hirota W, Kimura H

机构信息

Department of Oral & Maxillofacial Surgery, Hirosaki University School of Medicine, Japan.

出版信息

Int J Oral Maxillofac Surg. 2000 Jun;29(3):201-6.

Abstract

Osteoradionecrosis (ORN) of the mandible can arise following therapeutic radiotherapy for head and neck cancer. The incidence is quoted as 10-15%. Conservative and surgical therapies used for ORN have included vascularized osteocutaneous flap transfers, hyperbaric oxygen and ultrasound therapy. We have used an omental transfer for ORN without a segmental resection. We wrapped the affected mandible within the omentum in order to promote revascularization and neocellularity. Four patients suffering from ORN have undergone omental transfers. Two cases developed pathologic fractures postoperatively that were successfully treated by conservative management. In all cases, the patients' intractable pain improved, and no patient showed recurrence of ORN or wound dehiscence. Postoperative bone scintigrams showed the same degree of accumulation in the lesion as in normal adjacent bone. These results demonstrate the effectiveness of omental transfer and suggest that omental transfer has a promising place in the management of ORN.

摘要

下颌骨放射性骨坏死(ORN)可在头颈部癌症的治疗性放疗后发生。其发病率据报道为10% - 15%。用于ORN的保守和手术治疗方法包括带血管蒂的骨皮瓣转移、高压氧和超声治疗。我们使用网膜转移治疗ORN,而不进行节段性切除。我们将受影响的下颌骨包裹在网膜内,以促进血管再生和新细胞形成。四名患有ORN的患者接受了网膜转移。两例术后发生病理性骨折,经保守治疗成功治愈。在所有病例中,患者难以忍受的疼痛均有所改善,且无一例患者出现ORN复发或伤口裂开。术后骨闪烁扫描显示病变部位与相邻正常骨的放射性聚集程度相同。这些结果证明了网膜转移的有效性,并表明网膜转移在ORN的治疗中具有广阔的应用前景。

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