Shapiro M, Smith K J, James W D, Giblin W J, Margolis D J, Foglia A N, McGinley K, Leyden J J
Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
J Clin Microbiol. 2000 Sep;38(9):3174-8. doi: 10.1128/JCM.38.9.3174-3178.2000.
A cross-sectional quantitative study of cutaneous bacterial and yeast flora at seven body sites in 99 human immunodeficiency virus-seropositive and 50 seronegative military personnel was performed. Statistically significant differences in carriage rates were only observed for Staphylococcus aureus on the foreheads of seropositive individuals. Seronegative individuals demonstrated staphylococcal carriage rates 1.3 to 2 times as great as those of historical controls (defined as healthy individuals not receiving any medications) at five of six body sites. We conclude that seropositive military personnel do not exhibit statistically significant elevations in densities and carriage rates of the microorganisms examined (except Staphylococcus aureus), relative to seronegative individuals. Seropositive individuals may be predisposed to staphylococcal carriage. The elevated staphylococcal carriage rates of military personnel undergoing basic training warrants a formal evaluation of the impact of training exercises on cutaneous flora. The information gained may serve to limit the spread of infection during training exercises and battlefield conditions.
对99名人类免疫缺陷病毒血清阳性和50名血清阴性的军事人员的七个身体部位的皮肤细菌和酵母菌菌群进行了横断面定量研究。仅在血清阳性个体的前额上观察到金黄色葡萄球菌的携带率存在统计学显著差异。血清阴性个体在六个身体部位中的五个部位表现出葡萄球菌携带率是历史对照（定义为未接受任何药物治疗的健康个体）的1.3至2倍。我们得出结论，相对于血清阴性个体，血清阳性军事人员在所检测的微生物（金黄色葡萄球菌除外）的密度和携带率方面没有统计学显著升高。血清阳性个体可能易患葡萄球菌携带。接受基础训练的军事人员葡萄球菌携带率升高，有必要对训练演习对皮肤菌群的影响进行正式评估。所获得的信息可能有助于限制训练演习和战场条件下的感染传播。
