Skyrme R J, Fenn N J, Jones A R, Bowsher W G
Departments of Urology and Radiology, Royal Gwent Hospital, Newport, UK.
BJU Int. 2000 Sep;86(4):482-5. doi: 10.1046/j.1464-410x.2000.00786.x.
To determine the incidence of testicular microlithiasis in men presenting for testicular ultrasonography, to identify any associated pathology (with particular reference to testicular neoplasia) and to report the follow-up of those patients in whom testicular microlithiasis was identified.
In this retrospective study, the results of all testicular ultrasonography undertaken between July 1995 and March 1998 in a district general hospital were reviewed. The records of all patients diagnosed ultrasonographically to have testicular microlithiasis were retrieved and the pathology database was accessed for all testicular tumours diagnosed in the same period.
During the study period 2215 scans were taken; 34 cases of testicular microlithiasis were identified, giving an incidence of 1.4%. Thirty-one testicular tumours were removed during the same period. Of the 34 cases with testicular microlithiasis, five had histologically confirmed testicular tumours (15%). The incidence of testicular tumours in the scans showing no microlithiasis was 26 in 2181 (1.1%). The differential incidence of tumours in the two groups is statistically significant (P < 0.001, chi-square analysis). Patients with testicular microlithiasis but no tumour were followed up for a median (range) of 41 (19-54) months; no interval tumours have developed to date.
This study confirms an incidence of testicular microlithiasis comparable with that in other reported series, albeit in a selected population. There was a strong association between testicular microlithiasis and testicular tumours. Whether this is a causal relationship has yet to be determined. Careful clinical and ultrasonographic follow-up of these patients is therefore recommended until the significance of testicular microlithiasis is clear.
确定接受睾丸超声检查的男性中睾丸微石症的发病率，识别任何相关病变（尤其涉及睾丸肿瘤），并报告确诊为睾丸微石症患者的随访情况。
在这项回顾性研究中，回顾了1995年7月至1998年3月间在一家地区综合医院进行的所有睾丸超声检查结果。检索了所有经超声诊断为睾丸微石症患者的记录，并查阅了同期诊断的所有睾丸肿瘤的病理数据库。
在研究期间共进行了2215次扫描；确诊34例睾丸微石症，发病率为1.4%。同期切除了31例睾丸肿瘤。在34例睾丸微石症患者中，5例经组织学确诊为睾丸肿瘤（15%）。在未显示微石症的扫描中，睾丸肿瘤的发病率为2181例中有26例（1.1%）。两组肿瘤的发病率差异具有统计学意义（P<0.001，卡方分析）。对无肿瘤的睾丸微石症患者进行了中位（范围）41（19 - 54）个月的随访；迄今为止未出现间隔期肿瘤。
本研究证实睾丸微石症的发病率与其他报道系列相当，尽管是在特定人群中。睾丸微石症与睾丸肿瘤之间存在密切关联。这是否为因果关系尚待确定。因此，建议对这些患者进行仔细的临床和超声随访，直至睾丸微石症的意义明确。
