[慢性阻塞性支气管炎和支气管哮喘患者支气管黏膜的比较形态学特征]
[Comparative morphological characteristics of bronchial mucosa in patients with chronic obstructive bronchitis and bronchial asthma].
作者信息
Sokolov E I, Zykov K A, Veshkina A I, Shevelev V I, Mat'ko L Iu, Tsyplenkova V G
机构信息
N. A. Semashko Moscow Medical Stomatological Institute.
出版信息
Arkh Patol. 2000 Jul-Aug;62(4):31-7.
The material for histoultrastructural study was biopsies obtained by fibrobronchoscopy from 12 patients with endogenic bronchial asthma (BA) and 4 patients with chronic obstructive bronchitis (COB). The principal periods of affection in these diseases, the role of bronchial epithelium, effector cells of inflammation, nervous elements, smooth muscle cells, microcirculatory disturbances in patho- and morphogenesis of chronic obstructive pulmonary lesions are determined. The results indicate that BA develops due to disturbances of adaptive mechanisms being in some cases the issue of COB progression.
用于组织超微结构研究的材料是通过纤维支气管镜检查从12例内源性支气管哮喘（BA）患者和4例慢性阻塞性支气管炎（COB）患者身上获取的活检组织。确定了这些疾病的主要发病阶段、支气管上皮的作用、炎症效应细胞、神经成分、平滑肌细胞以及慢性阻塞性肺部病变病理和形态发生中的微循环障碍。结果表明，BA是由于适应性机制紊乱而发展的，在某些情况下是COB进展的问题。
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