Boo N Y, Chan B H
Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, Kuala Lumpur.
Med J Malaysia. 1998 Dec;53(4):358-64.
A prospective observational study was carried out over a seven month period in the neonatal intensive care unit (NICU) of a large Malaysian maternity hospital to determine the rate of blood transfusion and the incidence of transfusion reactions in newborn infants. During the study period, the rates of blood transfusion was 6.1% (n = 117) of NICU admission or 8.2 per 1,000 live births. The median birth weight of the infants who had received blood transfusion was 1,740 grams (range: 725-4,350), and their mean gestational age was 33.6 weeks (sd = 5.1, range = 24-41 weeks). The median age of infants when they first received blood transfusion was 4.0 days (range: 1-27 days). When compared with infants of birth weight between 3,000 and 3,499 grams, infants of birth weight less than 1,500 grams received significantly higher median number of transfusions per infant, (p < 0.001). The incidence of transfusion reaction was 2.7% (3/110) of all transfused infants or 1.3% (3/223) of all blood transfusions. Febrile nonhemolytic reaction was the only type of transfusion reaction detected during the study period. This study showed that transfusion reactions in newborn infants were not common.
在马来西亚一家大型妇产医院的新生儿重症监护病房（NICU）进行了一项为期七个月的前瞻性观察研究，以确定新生儿输血率和输血反应发生率。在研究期间，输血率为NICU入院人数的6.1%（n = 117），即每1000例活产中有8.2例。接受输血的婴儿中位出生体重为1740克（范围：725 - 4350克），平均胎龄为33.6周（标准差 = 5.1，范围 = 24 - 41周）。婴儿首次接受输血时的中位年龄为4.0天（范围：1 - 27天）。与出生体重在3000至3499克之间的婴儿相比，出生体重小于1500克的婴儿每例接受输血的中位次数显著更高（p < 0.001）。输血反应发生率为所有接受输血婴儿的2.7%（3/110）或所有输血的1.3%（3/223）。发热性非溶血性反应是研究期间检测到的唯一一种输血反应类型。这项研究表明新生儿输血反应并不常见。
