Khoo K L, Liew Y M, Tan H, Sambhi J S, Hatijah B A
Heart Foundation of Malaysia, Jalan Kia Peng, Kuala Lumpur.
Med J Malaysia. 1999 Mar;54(1):37-46.
The telephone survey of 2,526 hypertensive subjects showed 94% of the respondents were aware of the importance in controlling hypertension. Among these 504 were not on anti-hypertensive medication while the majority of 2,022 were currently on anti-hypertensive medication. Of those who were not on medication, 80% (n = 403) were found non-hypertensive on follow-up. The remaining 20% (n = 101) were confirmed hypertensive and were offered medication. However, 38 subjects refused to take medication and 63 subjects complied with medication but subsequently gave up. The main reasons for giving up medication included lack of motivation (38%), doctors' advice (20%), side effects (19%) and concern of side effects (10%). Of 2,022 hypertensive respondents who were currently on medication, almost half (44%, n = 890) required a change of medication due to side effects (40%, n = 356) or the blood pressure not controlled with the previous medication (33%, n = 294). Despite the change in medication, 42% (n = 150) still continued to suffer from some form of side effects. The information obtained from this survey suggested it is important to recommend some strategies to improve patient compliance. These strategies comprise of motivating the patient, improving medication with less side effects, improving potency and efficiency of medication, and reduction of cost in medication. In addition, convenient blood pressure monitoring such as home blood pressure monitoring is also encouraged.
对2526名高血压患者进行的电话调查显示，94%的受访者意识到控制高血压的重要性。其中504人未服用抗高血压药物，而大多数（2022人）目前正在服用抗高血压药物。在未服药的人群中，80%（n = 403）在随访中被发现血压正常。其余20%（n = 101）被确诊为高血压，并被提供了药物治疗。然而，38名受试者拒绝服药，63名受试者服药但随后放弃。放弃服药的主要原因包括缺乏动力（38%）、医生建议（20%）、副作用（19%）和担心副作用（10%）。在2022名目前正在服药的高血压受访者中，近一半（44%，n = 890）因副作用（40%，n = 356）或之前的药物无法控制血压（33%，n = 294）而需要更换药物。尽管更换了药物，仍有42%（n = 150）继续遭受某种形式的副作用。从这项调查中获得的信息表明，推荐一些提高患者依从性的策略很重要。这些策略包括激励患者、使用副作用较小的药物、提高药物的效力和效率以及降低药物成本。此外，还鼓励进行方便的血压监测，如家庭血压监测。
