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哌甲酯对不同程度多动行为中感觉知觉的影响。

The effect of methylphenidate on sensory perception in varying degrees of hyperkinetic behaviour.

作者信息

Butter H J, Lapierre Y D

出版信息

Dis Nerv Syst. 1975 Jun;36(6):286-8.

PMID:1097220
Abstract

In a double-blind study of methylphenidate, hyperkinetic children of varying levels of age and degree of hyperactivity were assessed on subtests of the Illinois Test of Psycholinguistic Ability (ITPA). The ITPA was supplemented with a combination of monosensory, bisensory, and trisensory stimuli presentations. Methylphenidate improved the ITPA's visual, auditory and tactile age scores of children who exhibited a more marked degree of hyperkinetic behaviour. That improvement was also observed in the recognition of sensory stimuli presented in a monosensory fashion. Similarly, the children with a more marked degree of hyperkinesis improved their stimuli recognition rate significantly on methylphenidate when stimuli were presented to bisensory and trisensory perceptual modalities simultaneously. It was concluded that drug improvement on sensory perception seemed to be more related to the degree of hyperkinetic behavior manifested than to chronological age. Further research of degree of hyperkinesis, age-level, sensory modality and drug administration was suggested.

摘要

在一项关于哌甲酯的双盲研究中,对不同年龄和多动程度的多动症儿童进行了伊利诺伊心理语言能力测验(ITPA)的分测验评估。ITPA还补充了单感觉、双感觉和三感觉刺激呈现的组合。哌甲酯提高了表现出更明显多动行为程度的儿童在ITPA视觉、听觉和触觉年龄得分。在以单感觉方式呈现的感觉刺激识别方面也观察到了这种改善。同样,当刺激同时呈现给双感觉和三感觉感知模式时,多动程度更明显的儿童在服用哌甲酯后其刺激识别率显著提高。得出的结论是,药物对感觉知觉的改善似乎与所表现出的多动行为程度的关系比与实际年龄的关系更大。建议对多动程度、年龄水平、感觉模式和药物给药进行进一步研究。

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