利什曼原虫膜转运蛋白的遗传学与生物化学
Genetics and biochemistry of Leishmania membrane transporters.
作者信息
Landfear S M
机构信息
Department of Molecular Microbiology and Immunology, Oregon Health Sciences University, Portland 97201, USA.
出版信息
Curr Opin Microbiol. 2000 Aug;3(4):417-21. doi: 10.1016/s1369-5274(00)00114-4.
Abstract
The ability to clone and functionally express genes encoding membrane transporters in Leishmania and related parasitic protozoa has illuminated the processes whereby these parasites acquire nutrients from their hosts. It is now possible to probe the physiological functions of these permeases and investigate their role in drug delivery and resistance.
摘要
在利什曼原虫及相关寄生原生动物中克隆并功能性表达编码膜转运蛋白的基因的能力，阐明了这些寄生虫从宿主获取营养的过程。现在有可能探究这些通透酶的生理功能，并研究它们在药物递送和耐药性中的作用。
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