Hirschfeld J
Hum Hered. 1975;25(2):144-51. doi: 10.1159/000152719.
A fairly uncomplicated T4 universe does give rise to a considerably complicated simple-complex image with several complexities regularly observed together in many immunogenetic systems. The present model thus 'explains' absence of antithetical alleles, absence of 'dosage' effects, presence of considerable quantitative variations of 'one and the same antigen' and peculiar 'non-autoantibodies'. These phenomena are exemplified for the Rh system with regard to the D--Du antigens, absence of d antigens, absence of clear-cut dosage between D/D and D/D and D/d samples as well as anti-D formation in seemingly 'normal Rh(+)' individuals.
一个相当简单的T4总体确实会产生一个相当复杂的简单-复杂图像，在许多免疫遗传系统中经常会同时观察到几种复杂性。因此，目前的模型 “解释了” 对立等位基因的缺失、“剂量” 效应的缺失、“同一抗原” 存在相当大的数量变异以及特殊的 “非自身抗体”。关于D--Du抗原、d抗原的缺失、D/D和D/D以及D/d样本之间缺乏明确的剂量关系以及在看似 “正常Rh(+)” 个体中形成抗-D等现象，以Rh系统为例进行了说明。
